Recombinant Mouse HLADG/CD74 Protein(C-mFc-6His)

Elabscience

Size

10µg

Catalog No.

PKSM041039-10µg

Price

203 EUR

Background

Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.

Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Stability and Storage

Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months

Synonym

HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; CD74; Cluster of Differentiation 74

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Purity

>95% as determined by reducing SDS-PAGE.

Source

Recombinants or rec. proteins

Sequence

Gln56-Leu215

Latin name

Mus musculus

Group

recombinants

Expressed Host

Human Cells

Fusion tag

C-mFc-6His

AP Mol Mass

45-55 kDa

Accession

P04441-2

Mol Mass

44.5 kDa

Activity

NA